A story on breast cancer I

Although a lot of disadvantages of insomnia, but at least it is a benefit to you a quiet extra hours during the day so that you can do no time or no mood to do. . . For example updated blog:)

Because my thesis that women involved in breast cancer treatment and prevention factors research, I have to know the uw a professor of genome science ---- Mary Clair, she is to carry out the genetic factors of breast cancer experts, but to I feel more like an old lady like Xiankan life, according to fashion point of view, I think she has unlimited enthusiasm nosy science behind the story, this is actually very interesting!

Today she spoke to me a very funny story: that she is in Gangjin uw when the assistant professor, she decided to engage in genetic breast cancer research, and his fight for his life to the first NIH funding. For those who engage in genetic diseases, the most important thing is to find spectrum of family data, which means you have to find some typical of a genetic history of the family, then as many as possible to collect the entire family, everyone (including the one to grandparents And down to various branches of the child) cases records and DNA samples of their collection (the best example is probably the family spectrum hemophilia record of the British royal family:). Of course we can imagine, this is very difficult for the data, so at the beginning of Mary Clair only three-on-hand in this family! In her into such a predicament, just to catch up with NIH birthday, when the Seattle intend to do a television interview programs, inform the public of the NIH in support of what kind of projects; Pianqiao Mary Clair to catch up with friends on television, therefore They find her, gave her 90 seconds of the time, Mary Clair used by 90 seconds that we are now doing breast cancer research, if your whole family, there are more than four cases of breast cancer patients, please contact us, Also announced on the screen of her phone number!


Has been here, the stories are boring! But the most dramatic colors happened in a programme broadcast that night, the night of living in California, Mrs. Reagan (Nancy Reagan) had been diagnosed with breast cancer! National overnight sensation, all the people all of a sudden concern from the beginning of breast cancer, and this 90 seconds of television programs from Seattle to California was by television, After resale, even in the final to the ABC show, which Xiazai Mary Clair phone Numbers became widely known! The next year, Mary Clair laboratory in the whole of the calls and busy throughout the country to collect data and samples, even until the last they have accumulated more than 100 such families! Mary Clair has talked about this or Meifeisewu, she said to me, more than 100 families have such data, she wrote a paper record for repeated, Wuwangbusheng, NIH is the icing on the cake of course, continue to provide adequate funding, and she herself is also In a wild, and then to assistant to associate professor, she said here will, of course, a sigh: "I owe all these to Mrs. Reagan!"


If this story to end here, of course, we all sigh in Mary Clair's lucky; But Mary Clair section of the most talked about is actually more lovable side of it!


In that over 100 families, most of a family for her study provides the most powerful data, but this family is very unfortunate! It originated in the United Kingdom, and later immigrants to the U.S. central plains, the whole family a total of four generations of existing data, every generation has many children, but no one on a university, not the high level of education, life is not wealthy, the most tragic The family is the most women died of breast cancer, and the average age of onset was less than 30-year-old! Breast cancer on the family of a woman as Chen Chen Yin pressure in the dark clouds overhead, it can be said in this home, a girl born from that moment onwards, she began to worry about their breast cancer when there will be. . .


Mary Clair this with a female patient contact for some time, this woman physically very bad, because her time in the 37-year-old was diagnosed with breast cancer and she has three children, the only daughter has just 21-year-old; Mary Clair She collected the samples, they persuaded her to collect samples of this little girl was found, although only 21 years old, but she has breast in a small amount of cancerous cells in this little girl was seven eleven, fundamental No health insurance, while her husband has abandoned her because of this. . .


Mary Clair then told me that she felt such a family, such a child to bear too much death, life is too sad for them too heavy, so her family made up the story also written out in Each conference, every seminar on the use of this story at the end of her research to progress, finally gave donations to a fund that one, so that those infected persons to accept the surgery as soon as possible, so that a future birth to a girl Regular inspections to go to the hospital, the first to take the treatment! Mary Clair most lovable to me that she is the Yige Jin stressed that this little girl was later remarry, found a much much better man!


Story mentioned here, in fact, there is a mystery not opened, why this one will be like a curse, like so unfortunately it » Finally, after almost five years of research, Mary Clair found that everything was all because it is one of the great-grandfather! He's a genetic mutation of a site, this mutation, the man can only be a small flaw, it would slightly increase the risk of colorectal cancer and pancreatic cancer, but when this
unfortunate gene passed on his daughter and her daughter Daughter, this small flaw will become fatal. . . This gene is also now notorious BRCA1, which is unfortunate families also found that BRCA1 to become contributors!


This is the story, Mary Clair like to add a conclusion, she felt that this story is an excellent example of how science is needed on the help of the media, need the support of the community, and how scientific feedback to the media, how can the return of those who helped Of our people and the whole of society and the future. . . .

For me, these noble Piequ the significance of education, at least I think this is an excellent example of what can be described to the silly point of life science research and the atmosphere and the legendary colors. . .